Semax 5 mg
Semax is a synthetic heptapeptide developed at the Moscow State University Institute of Molecular Genetics in the 1990s. It is the most-studied compound in the Russian cognitive-research literature, with applications spanning neuroprotection research, BDNF-pathway studies, and post-stress cognitive-recovery protocols. It is on the Russian Federation's essential-medicines list.
What Semax is
Semax is the synthetic analogue of a fragment of adrenocorticotropic hormone (ACTH 4-10) extended with the prolyl-glycyl-proline tripeptide on its C-terminus. The natural ACTH fragment has neuromodulatory activity but rapid degradation in plasma; the prolyl-glycyl-proline extension makes the molecule much more stable, which is what enables practical research use. The full sequence is Met-Glu-His-Phe-Pro-Gly-Pro.
What the research literature covers
Published research on Semax spans BDNF (brain-derived neurotrophic factor) and NGF (nerve growth factor) expression in cortical and hippocampal tissue, neuroprotection in ischaemic models, cognitive-recovery research after experimental stroke in rodents, and broader neuromodulation. Semax is officially approved in Russia for several clinical neurology indications — making it one of the few research peptides with a substantial human clinical-evidence base, even though the bulk of that evidence is in Russian-language literature less accessible to Western researchers.
How researchers typically use Semax
The standard research route is intranasal — Semax is one of the few neuropeptides with a well-established intranasal pharmacokinetic profile, which exploits direct nose-to-brain transport along the olfactory pathway and bypasses both the gut and the blood-brain barrier. Research protocols typically dose 2-3 times daily during active research windows. Researchers studying acute cognitive-stress recovery use Semax during the recovery window; researchers studying broader cognitive-protection questions use longer cycles with rest periods.
Quality verification
Two-stage Wellness Labs verification: upstream ICH Q7 GMP manufacturing, independent HPLC analysis at a third-party US laboratory, ≥98% peak-area purity at λ=214 nm against pharmacopoeia reference standards. Each released batch ships with a Certificate of Analysis available through the research account.
In the semax range
Common questions
- Is Semax legal in the UAE?
- Semax is classified as a research compound in the UAE and is sold through standard wellness-supply channels. It is an approved medicine in the Russian Federation but is not licensed as a medicine in the UAE; sale is on the research-compound basis. Wellness Labs operates under standard UAE commercial trading rules with VAT compliance.
- How is Semax administered?
- The standard route is intranasal — a few drops or a metered spray of reconstituted solution into each nostril. Subcutaneous and oral routes have been studied but the intranasal route is the basis of the bulk of the research literature and is the route Russian clinical protocols use. Reconstitution and administration guidance accompanies every shipment.
- What is the typical research-protocol dose?
- Russian clinical protocols use doses in the 600-1500 mcg per day range (split across 2-3 administrations) for cognitive-protection contexts; lower doses (300-600 mcg per day) are common in research-community protocols for general neuromodulation. Researchers calibrate to their own protocol design.
- Semax vs Selank — what is the difference?
- Semax targets cognitive and neuroprotection axes (BDNF/NGF expression, neuromodulation). Selank — the sister compound developed at the same Russian research group — targets anxiolytic and immunomodulatory axes. Researchers studying composite questions covering both cognitive performance and stress-anxiety frequently pair them.
- How quickly does Semax show effects?
- Published research suggests acute neuromodulatory effects within the first administration window (subjective cognitive effects reported by researchers in the first 30-60 minutes). BDNF/NGF expression changes accumulate over 7-14 days of consistent administration. Longer-term neuroprotective effects are the slow-and-steady component over months.
- How is Semax stored?
- Lyophilised Semax is ambient-temperature stable in transit. Long-term storage at -20 °C protected from light is recommended. After reconstitution, refrigerated storage with appropriate handling per the supplied protocol; effective storage life of reconstituted Semax solution is approximately 2-4 weeks under correct conditions.
- How fast is delivery in the UAE?
- Same-day in Dubai, next-business-day across the UAE. GCC in 3-5 business days.
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