hGH C-Terminal Fragment · Lipid-Metabolism Research

AOD-9604 5 mg — Research Consultation

AOD-9604 is a synthetic 15-amino-acid peptide based on the C-terminal 176-191 fragment of human growth hormone. Published preclinical research describes effects on lipid metabolism through pathways distinct from full-length hGH's anabolic and glucose-regulatory signalling. This page summarises the mechanism and links you into a Nour-led research consultation.

What AOD-9604 is

AOD-9604 (Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe) is the C-terminal 176-191 segment of human growth hormone with an added N-terminal tyrosine for radio-labelling. The research hypothesis is that this fragment retains the lipid-metabolism signalling associated with the parent hormone's C-terminal region while being decoupled from the IGF-1 / anabolic / glucose-regulatory pathways mediated by other parts of full-length hGH.

What the published literature covers

Preclinical research describes AOD-9604 effects on lipolysis in adipocyte cell culture, lipid-metabolism endpoints in rodent feeding studies, and the absence of effect on glucose tolerance or IGF-1 levels at active research doses. Human-research is limited — a small early-phase clinical literature exists, but most published evidence is preclinical.

Quality verification

Lyophilised AOD-9604 manufactured under ICH Q7 GMP standards. Independent HPLC verification at a US-based third-party laboratory, ≥98% peak-area purity. COA available through the in-chat consultation.

Common research questions

Is AOD-9604 legal in the UAE?
AOD-9604 is classified as a research compound in the UAE and is sold through standard wellness-supply channels with VAT compliance applied to every dispatch.
What dose ranges does the published research describe?
Preclinical research uses dose ranges that scale with model species. In the grey-research community, subcutaneous protocols of 250-500 mcg daily are commonly described, often for cycles of 4-12 weeks. Published human-research evidence is too limited to support a consensus protocol.
Does AOD-9604 act like full-length growth hormone?
No. The published research hypothesis is that AOD-9604 retains a specific subset of hGH signalling — that associated with the C-terminal region's lipid-metabolism effects — while being decoupled from the IGF-1 and glucose-regulatory pathways. This is the basis for studying the fragment separately from the parent hormone.
How is purity verified?
HPLC peak-area purity (≥98%) at a US-based third-party laboratory. COA available through the chat.
Shelf life and storage?
Lyophilised powder is ambient-temperature stable in transit; -20°C long-term storage; refrigerated post-reconstitution per the supplied protocol.
How fast is delivery in the UAE?
Same-day delivery within Dubai, next-business-day across the rest of the UAE.

Peer-reviewed references

  1. [1]Heffernan et al. — AOD-9604 lipolytic activity in vitro (PubMed)
  2. [2]Ng & Bornstein — hGH C-terminal fragment research overview
  3. [3]Stier et al. — AOD-9604 preclinical pharmacology review

Related consultations

Talk to Nour about your research protocol

Nour reads the peer-reviewed literature and walks you through what each compound is best suited for. English or Arabic, inside the chat.