Kisspeptin-10 5 mg — Research Consultation
Kisspeptin-10 is the 10-amino-acid C-terminal fragment of the endogenous KISS1 gene product and a high-affinity agonist of the kisspeptin receptor (KISS1R, formerly GPR54). Published research describes its role as the principal upstream regulator of hypothalamic GnRH neuron activity.
What Kisspeptin-10 is
The KISS1 gene encodes a 145-amino-acid precursor that is processed to several biologically-active fragments. Kisspeptin-10 (sometimes "kp-10" or metastin 45-54) is the shortest fragment that retains full KISS1R receptor activity. The published research identifies kisspeptin signalling as the upstream regulator of GnRH neuron firing in the hypothalamus.
What the published literature covers
Published research describes KISS1R receptor pharmacology, kisspeptin pharmacokinetics in human pharmacology studies, downstream GnRH and gonadotropin pulse-frequency endpoints, and the role of kisspeptin signalling in puberty-related and neuroendocrine research. Kisspeptin-10 has a short plasma half-life — minutes rather than hours.
Quality verification
Lyophilised Kisspeptin-10 manufactured under ICH Q7 GMP standards. Independent HPLC verification at a US-based third-party laboratory, ≥98% peak-area purity. COA available through the in-chat consultation.
Common research questions
- Is Kisspeptin-10 legal in the UAE?
- Kisspeptin-10 is classified as a research compound in the UAE and is sold through standard wellness-supply channels with VAT compliance applied to every dispatch.
- What dose ranges does the published research describe?
- Published human pharmacology research uses microgram-range doses administered as an IV bolus or short subcutaneous infusion, because of kisspeptin's very short half-life. Grey-research protocols vary widely and the published evidence base for chronic subcutaneous administration is limited.
- Kisspeptin-10 vs. Kisspeptin-54?
- Both are biologically-active fragments of the KISS1 precursor. Kisspeptin-10 is the minimum-length fragment with full receptor activity. Kisspeptin-54 has a longer plasma half-life. Both are studied in the published pharmacology research; choice depends on the research question.
- What does KISS1R signalling do downstream?
- In the published literature, KISS1R agonism on hypothalamic GnRH neurons increases their firing rate, which propagates downstream to anterior pituitary gonadotropin release. The kisspeptin → GnRH → gonadotropin axis is the principal upstream signalling pathway described in the research.
- How is purity verified?
- HPLC peak-area purity (≥98%) at a US-based third-party laboratory. COA available through the chat.
- Shelf life and storage?
- Lyophilised powder is ambient-temperature stable in transit; -20°C long-term storage; refrigerated post-reconstitution per the supplied protocol.
- How fast is delivery in the UAE?
- Same-day delivery within Dubai, next-business-day across the rest of the UAE.
Peer-reviewed references
Related consultations
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