GHRH + GHRP Blend · Combined-Signalling Research

CJC-1295 (no-DAC) + Ipamorelin Blend — Research Consultation

A combined-blend research preparation of CJC-1295 without DAC (a tetra-substituted GHRH(1-29) analogue) and Ipamorelin (a selective ghrelin-receptor agonist). Published research describes the additive growth-hormone-release effect produced by simultaneous GHRH-receptor and ghrelin-receptor activation.

What this blend is

The combined research preparation pairs CJC-1295 (no-DAC) — a stabilised GHRH(1-29) analogue with four amino-acid substitutions for protease resistance — with Ipamorelin, a five-amino-acid selective ghrelin-receptor agonist. The two compounds act on different receptors and produce additive growth-hormone release in published pharmacology research.

GHRH + GHRP — combined-signalling research model

GHRH analogues bind the GHRH receptor on somatotroph cells. GHRPs bind the ghrelin (GHS-R1a) receptor on the same cells. Published research shows that simultaneous activation of both receptor pathways produces a larger GH pulse than either alone — the basis for the combined-signalling research model used in many human pharmacology studies.

CJC-1295 with DAC vs. without DAC

The DAC (Drug Affinity Complex) variant of CJC-1295 has a maleimido-propionic-acid tag that covalently binds serum albumin, producing a longer half-life. The no-DAC variant retains the four stabilising substitutions without the albumin tag, giving a shorter pharmacokinetic profile that more closely matches Ipamorelin's. Researchers studying combined GHRH + GHRP pharmacology typically use the no-DAC variant.

Quality verification

Lyophilised blend manufactured under ICH Q7 GMP standards. Independent HPLC verification at a US-based third-party laboratory confirms peak-area purity of both peptides individually. COA available through the in-chat consultation.

Common research questions

Is the CJC-1295 + Ipamorelin blend legal in the UAE?
Both peptides are classified as research compounds in the UAE and are sold through standard wellness-supply channels with VAT compliance applied to every dispatch.
What dose ranges does the published research describe?
Published pharmacology research and grey-research protocols commonly describe 100-300 mcg of each peptide per administration, two-to-three times daily, in cycles of 8-12 weeks followed by a rest period. The blend formulation allows both peptides to be drawn in a single injection.
Why no-DAC instead of with-DAC?
No-DAC matches Ipamorelin's pharmacokinetic profile, so both peptides act within the same time window. The with-DAC variant lasts much longer (5-10 days), which is incompatible with the pulsatile GH-release research model the blend is designed for.
Why pair instead of separate?
GHRH analogues and GHRPs act on different receptors and produce additive GH release in the published literature. The paired protocol is the standard combined-signalling research model. The blend simplifies administration relative to drawing two compounds separately.
How is purity verified?
HPLC peak-area purity (≥98%) at a US-based third-party laboratory for both peptides. COA available through the chat.
Shelf life and storage?
Lyophilised powder is ambient-temperature stable in transit; -20°C long-term storage; refrigerated post-reconstitution per the supplied protocol.
How fast is delivery in the UAE?
Same-day delivery within Dubai, next-business-day across the rest of the UAE.

Peer-reviewed references

  1. [1]Sigalos & Pastuszak — GHRH/GHRP combination pharmacology (PubMed)
  2. [2]Teichman et al. — CJC-1295 pharmacokinetics in healthy adults
  3. [3]Raun et al. — Ipamorelin selective GH secretagogue characterisation

Related consultations

Further reading

Talk to Nour about your research protocol

Nour reads the peer-reviewed literature and walks you through what each compound is best suited for. English or Arabic, inside the chat.